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교수진

이상기 교수

Sangkee Rhee

전공구조생물학
주소200동 7117호
연락처02-880-4647
이메일srheesnu@snu.ac.kr
학력사항

B.S. Seoul National University, Korea, 1983

M.S. Seoul National University, Korea, 1985

Ph.D. University of Iowa, USA, 1994
경력

Visiting/Research Fellow, NIH, USA, 1994-1999

수상

과학기술부 연구개발사업 우수 연구성과 50선 (2007)

연구 관심분야

단백질 구조 및 기능 Protein Structure and Function

X-선 결정학 X-ray Crystallography

효소 Enzymes

병원성 단백질 Proteins in Pathogenesis

식물호르몬 신호전달 단백질 Proteins in Plant hormone Signal-Transduction

대표 논문

Chung, J., Goo, E., Yu, S., Choi, O., Lee, J., Kim, J., Kim, H., Igarashi, J., Suga, H., Moon, J.S., Hwang, I., and Rhee, S. (2011) Small-molecule inhibitor binding to an N-acyl-homoserine lactone synthase. Proc. Natl. Acad. Sci. USA 108:12089-12094

Jung, W.-S., Lee, J., Kim, M.-I., Ma, J., Nagamatsu, T., Goo, E., Kim, H., Hwang, I., Han, J., and Rhee, S. (2011) Structural and functional analysis of phytotoxin toxoflavin-degrading enzyme. PLoS ONE 6, e22443.

Cho, J.-H., Jung, D.-K., Lee, K., and Rhee, S. (2009) Crystal structure and functional analysis of the extradiol dioxygenase LapB from a long-chain alkylphenol degradation pathway in Pseudomonas. J. Biol. Chem. 284:34321-34330

Kim, K., Kim, M.I., Chung, J., Ahn, J.H., and Rhee, S. (2009) Crystal structure of metal-dependent allantoinase from Escherichia coli. J. Mol. Biol. 387: 1067-1074

Cho, J.H., Park, Y., Ahn, J.H., Lim, Y., and Rhee, S. (2008) Structural and functional insights into O-methyltransferase from Bacillus cereus. J. Mol. Biol. 382: 987-997.

Kim, M.I., Kim, H.S., Jung, J., and Rhee, S. (2008) Crystal structure and mutagenesis of sucrose hydrolase from Xanthomonas axonopodis pv. glycines: Insight into the exclusively hydrolytic amylosucrase fold. J. Mol. Biol. 380: 636-647.

Kim, K., Park, J., and Rhee, S. (2007) Structural and functional basis for (S)-allantoin formation in the ureide pathway. J. Biol. Chem. 282: 23457-23464.

Jung, W.S., Hong, C.K., Lee, S., Kim, C.S., Kim, S.J., Kim, S.I, and Rhee, S. (2007) Structural and functional insights into intramolecular fructosyl transfer by inulin fructotransferase. J. Biol. Chem. 282: 8414-8423.

Jung, D.K., Lee, Y., Park, S.G., Park, B.C., Kim, G.H. and Rhee, S. (2006) Structural and functional analysis of PucM, a hydrolase in the ureide pathway and a member of transthyretin-related protein family. Proc. Natl. Acad. Sci. USA 103: 9790-9795

Kim, K., Kim, H.J., Oh, D.K., Cha, S.S., and Rhee, S. (2006) Crystal structure of D-psicose 3-epimerase from Agrobacterium tumefaciens and its complex with true substrate D-fructose: a pivotal role of metal in catalysis, an active site for the non-phosphorylated substrate, and its conformational changes. J. Mol. Biol. 361: 920-931.